This workbook is for community-based organizations, public health practitioners, and community health partners seeking to create health equity by addressing the social determinants of health. It was created to encourage and support the development of new, and the expansion of existing, initiatives and partnerships to address the social determinants of health inequities. Content is drawn from Social Determinants of Disparities in Health: Learning from Doing, a forum sponsored by the U.S. Centers for Disease Control and Prevention in October 2003. Forum participants included representatives from community organizations, academic settings, and public health practice who have experience developing, implementing, and evaluating interventions to address conditions contributing to health inequities. The workbook reflects the views of experts from multiple arenas, including local community knowledge, public health, medicine, social work, sociology, psychology, urban planning, community economic development, environmental sciences, and housing. It is designed for a wide range of users interested in developing initiatives to increase health equity in their communities. The workbook builds on existing resources and highlights lessons learned by communities working toward this end. Readers are provided with information and tools from these efforts to develop, implement, and evaluate interventions that address social determinants of health equity.